ALN 5288
Alternative Names: ALN-5288Latest Information Update: 28 Nov 2025
At a glance
- Originator Alnylam Pharmaceuticals
- Class Antidementias; Drug conjugates; Small interfering RNA
- Mechanism of Action Protein expression modulators; RNA interference
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Alzheimer's disease
Most Recent Events
- 15 Oct 2025 Phase-I clinical trials in Alzheimer's disease in Canada (Intrathecal) (NCT07214727) (CTIS2025-522582-30-00)
- 14 Oct 2025 Preclinical trials in Alzheimer's disease in USA (Intrathecal)
- 09 Oct 2025 Alnylam Pharmaceuticals plans a phase I trial for Alzheimer's disease (AD) in Canada, Netherlands, Spain, United Kingdom (Intrathecal), in October 2025 (NCT07214727; CTIS2025-522582-30-00)