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Neridronate - Ambros Therapeutics

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Drug Profile

Neridronate - Ambros Therapeutics

Alternative Names: AMBTX-01

Latest Information Update: 22 Dec 2025

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At a glance

  • Originator Ambros Therapeutics
  • Class Analgesics; Antihypercalcaemics; Bisphosphonates; Calcium regulators; Osteoporosis therapies; Small molecules
  • Mechanism of Action Bone resorption factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Complex regional pain syndromes
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Complex regional pain syndromes

Most Recent Events

  • 16 Dec 2025 Ambros Therapeutics plans a phase III CRPS-RISE trial in Complex regional pain syndromes in USA (IV, Infusion) (NCT07210515) (Ambros Therapeutics pipeline, October 2025)
  • 17 Oct 2025 Neridronate - Ambros Therapeutics receives Breakthrough Therapy status for Complex regional pain syndromes in USA (Ambros Therapeutics pipeline, October 2025)
  • 15 Oct 2025 Phase-I/II trials in Complex regional pain syndromes in USA (IV) (Ambros Therapeutics pipeline, October 2025)

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