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af 001

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Drug Profile

af 001

Alternative Names: [211At]NaAt - Alpha Fusion; af-001; astatine-211 sodium astatide - Alpha Fusion; TAH 1005

Latest Information Update: 27 Dec 2025

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At a glance

  • Originator Alpha Fusion
  • Class Antineoplastics; Radioisotopes; Radiopharmaceuticals; Small molecules
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Thyroid cancer

Most Recent Events

  • 07 Nov 2025 Alpha Fusion initiates in a phase I trial for Thyroid cancer (Second-line therapy or greater, Metastatic disease) (IV) in Japan (jRCT2031250472)

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