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SIR 2501

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Drug Profile

SIR 2501

Alternative Names: SIR-2501

Latest Information Update: 10 Nov 2025

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At a glance

  • Originator Sironax
  • Developer Sironax Aus Pty
  • Class Neuroprotectants
  • Mechanism of Action SARM1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Neurodegenerative disorders

Most Recent Events

  • 10 Nov 2025 Sironax plans a phase Ib/IIa trial for Amyotrophic lateral sclerosis in China (CTR20253552)
  • 03 Nov 2025 Adverse events and pharmacodynamic data from a phase I trial in healthy volunteers presented at the Society for Neuroscience (SFN 2025)
  • 07 Apr 2025 Sironax Australia Pty completes a phase I trial in healty volunteers (In adults) (PO) in China and Australia (ACTRN12624000562572) .

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