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GPV 381

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Drug Profile

GPV 381

Alternative Names: GPV-381

Latest Information Update: 04 Jun 2026

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At a glance

  • Originator Denteric
  • Class Anti-inflammatories; Antidementias; Recombinant proteins
  • Mechanism of Action Bacterial toxin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Alzheimer's disease; Periodontitis

Most Recent Events

  • 28 May 2026 Phase-I clinical trials in Alzheimer's disease in Australia (IM, Injection) (ACTRN12625001260415)
  • 25 Mar 2026 US FDA approves IND application for GPV 381 in Periodontitis
  • 25 Mar 2026 Denteric plans a phase II trial for Periodontitis in USA

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