Drug Profile

Research programme: protein degraders - Opna Bio

Latest Information Update: 15 Dec 2025

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At a glance

Originator Opna Bio
Class Antineoplastics
Mechanism of Action CREB-binding protein degraders; EP300 protein degraders; IKZF1 protein degraders; IKZF3 protein degraders

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

08 Dec 2025 Opna Bio announces intention to submit an Investigational New Drug (IND) application in 2027
04 Nov 2025 Preclinical trials in Lymphoma in Switzerland (unspecified route)
04 Nov 2025 Preclinical trials in Multiple myeloma in Switzerland (unspecified route)

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