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EN 002

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Drug Profile

EN 002

Alternative Names: EN-002; In vivo HER2 targeting CAR cell therapy - Ensoma; Lineage-restricted multiplexed CAR-M, CAR-NK, CAR-T cell therapy - Ensoma

Latest Information Update: 25 May 2026

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At a glance

  • Originator Ensoma
  • Class Antineoplastics; Gene therapies; Immunotherapies; Viruses
  • Mechanism of Action Immunologic cytotoxicity; Macrophage replacements; Natural killer cell replacements; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 08 May 2026 Pharmacodynamics data from a preclinical trial in Solid tumours released by Ensoma
  • 04 Nov 2025 Preclinical trials in Solid tumours in USA (Parenteral) prior to November 2025
  • 04 Nov 2025 Pharmacodynamics data from a preclinical trial in Solid tumours released by Ensoma

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