Drug Profile

CGT 1145

Alternative Names: CGT-1145; JAK2V617F - Cogent Biosciences

Latest Information Update: 18 Jun 2026

Price :

$50 ^*

Note:

Adis is an information provider. We do not sell or distribute actual drugs.
Final gross price and currency may vary according to local VAT and billing address.
Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

Originator Cogent Biosciences
Class Antineoplastics
Mechanism of Action Janus kinase 2 inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Preclinical Myeloproliferative disorders

Most Recent Events

12 Jun 2026 Pharmacokinetics data from a preclinical trial in Myeloproliferative disorders released by Cogent Biosciences
31 Dec 2025 Cogent Biosciences has patent protection for CGT 1145
06 Dec 2025 Pharmacodynamics and adverse event data from a preclinical trial in Myeloproliferative disorders presented at the 67^th American Society of Hematology Annual Meeting and Exposition ((ASH-Hem-2025)

You need to be a logged in or subscribed to view this content

If your organization or you do not have a subscription, try one of the following:

Contacting your organization’s admin about adding this content to your AdisInsight subscription
Buying a PDF version of any individual profile
Request a free trial (opens in a new window)

If your organization has a subscription, there are several access options, even while working remotely:

Working within your organization’s network
Login with username/password or try to access via your institution
Persisted access using your organization’s identifier stored in your user browser for 90 days

For assistance, contact us at asktheexpert.adisinsight@springer.com