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GNS 3545

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Drug Profile

GNS 3545

Alternative Names: GNS-3545

Latest Information Update: 02 Dec 2025

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At a glance

  • Originator Genosco
  • Class Antifibrotics; Small molecules
  • Mechanism of Action Rho-associated kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Idiopathic pulmonary fibrosis

Most Recent Events

  • 14 Nov 2025 GNS 3545 is available for licensing as of 14 Nov 2025. http://www.genosco.com/m22.php?subCate=1
  • 12 Nov 2025 Phase-I clinical trials in Idiopathic pulmonary fibrosis (In volunteers) in USA (PO) (NCT07225296)
  • 03 Oct 2025 US FDA approves IND application for GNS 3545 in Idiopathic pulmonary fibrosis

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