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TSRA 196

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Drug Profile

TSRA 196

Alternative Names: TSRA-196

Latest Information Update: 27 Feb 2026

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At a glance

  • Originator Tessera Therapeutics
  • Class Gene therapies
  • Mechanism of Action Alpha 1-antitrypsin expression modulators; Gene expression modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Alpha 1-antitrypsin deficiency
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Alpha 1-antitrypsin deficiency

Most Recent Events

  • 23 Feb 2026 Phase-I/II clinical trials in Alpha 1-antitrypsin deficiency(IV) (NCT07227207)
  • 23 Feb 2026 TSRA 196 receives Fast Track designation for Alpha 1-antitrypsin deficiency [IV,Infusion] in USA
  • 23 Feb 2026 TSRA 196 receives Orphan Drug status for Alpha 1-antitrypsin deficiency in USA

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