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TSRA 196

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Drug Profile

TSRA 196

Alternative Names: TSRA-196

Latest Information Update: 04 Dec 2025

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At a glance

  • Originator Tessara Therapeutics
  • Class Gene therapies
  • Mechanism of Action Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Alpha 1-antitrypsin deficiency

Most Recent Events

  • 01 Dec 2025 Regeneron Pharmaceuticals and Tessera Therapeutics enters into a global collaboration to develop and commercialize TSRA 196 for Alpha-1 antitrypsin deficiency
  • 01 Dec 2025 Tessera Therapeutics plans to submit an IND along with multiple CTA filings for TSRA 196, with all submissions expected by the end of 2025
  • 17 Nov 2025 Preclinical trials in Alpha 1-antitrypsin deficiency in Australia (IV)

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