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BIIB 145

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Drug Profile

BIIB 145

Alternative Names: BIIB-145

Latest Information Update: 06 Mar 2026

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At a glance

  • Originator Biogen
  • Class Small molecules
  • Mechanism of Action Agammaglobulinaemia tyrosine kinase degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Multiple sclerosis

Most Recent Events

  • 31 Jan 2026 C4 Therapeutics and Biogen agree to co-develop BIIB 145 for Multiple myeloma
  • 18 Dec 2025 Phase-I clinical trials in Multiple sclerosis (In volunteers) in USA (PO) (NCT07225517)
  • 13 Nov 2025 Biogen plans a phase I trial (In volunteers) (PO), in December 2025 (NCT07225517)

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