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STLX 2012

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Drug Profile

STLX 2012

Alternative Names: Anti-IL1RAP mAb; STLX-2012

Latest Information Update: 28 Nov 2025

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At a glance

  • Originator Stelexis Therapeutics
  • Class Antifibrotics; Antineoplastics; Immunotherapies; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Interleukin-1 receptor accessory protein inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Acute myeloid leukaemia; Chronic myelomonocytic leukaemia; Myelodysplastic syndromes; Myelofibrosis; Systemic mastocytosis

Most Recent Events

  • 21 Nov 2025 Preclinical trials in Acute myeloid leukaemia in USA (IV), prior to November 2025 (Stelexis Therapeutics pipeline, November 2025)
  • 21 Nov 2025 Preclinical trials in Chronic myelomonocytic leukaemia in USA (IV), prior to November 2025 (Stelexis Therapeutics pipeline, November 2025)
  • 21 Nov 2025 Preclinical trials in Myelodysplastic syndromes in USA (IV), prior to November 2025 (Stelexis Therapeutics pipeline, November 2025)

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