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DF 5112

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Drug Profile

DF 5112

Alternative Names: DF-5112

Latest Information Update: 27 May 2026

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At a glance

  • Originator Dragonfly Therapeutics
  • Class Antifibrotics; Antipsoriatics; Antirheumatics; Immunotherapies; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Hidradenitis suppurativa; Primary biliary cirrhosis; Psoriatic arthritis; Rheumatoid arthritis; Systemic scleroderma

Most Recent Events

  • 18 May 2026 Early pharmacodynamics data from a phase I trial in Autoimmune disorders released by Dragonfly Therapeutics
  • 12 Jan 2026 Phase-I clinical trials in Hidradenitis suppurativa (In volunteers) in Australia (IV) (NCT07232121) (Dragonfly Therapeutics Pipeline, June 2026)
  • 12 Jan 2026 Phase-I clinical trials in Hidradenitis suppurativa (In volunteers) in Australia (SC) (NCT07232121) (Dragonfly Therapeutics Pipeline, June 2026)

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