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Cereblon E3 ligase modulator - Bristol Myers Squibb/Evotec SE

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Drug Profile

Cereblon E3 ligase modulator - Bristol Myers Squibb/Evotec SE

Latest Information Update: 02 Jan 2026

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At a glance

  • Originator Evotec SE
  • Developer Bristol-Myers Squibb; Evotec SE
  • Class
  • Mechanism of Action CRBN protein modulators; Ubiquitin protein ligase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Unspecified

Most Recent Events

  • 12 Nov 2025 Preclinical trials in Unspecified in Germany (unspecified route) before November 2025
  • 12 Nov 2025 US FDA approves IND application for an unspecified indication
  • 12 Nov 2025 Evotec SE plans a phase I clinical trial in 2026

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