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DEG 6498

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Drug Profile

DEG 6498

Alternative Names: DEG-6498

Latest Information Update: 02 Dec 2025

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At a glance

  • Originator Degron Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proteolysis
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 27 Nov 2025 Preclinical trials in Solid tumours in China (PO)
  • 24 Nov 2025 Degron Therapeutics plans a phase I trial for Solid tumours (Late-stage disease) in China (PO, Capsules) in November 2025 (NCT07244835) (CTR20254261)
  • 13 Nov 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Second-line therapy or greater) in China (PO) (NCT07244835)

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