Drug Profile

GenSci 143

Alternative Names: GenSci-143

Latest Information Update: 30 Jan 2026

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At a glance

Originator GeneScience Pharmaceuticals
Class Antineoplastics; Bispecific antibodies; Drug conjugates; Immunoconjugates
Mechanism of Action DNA topoisomerase I inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Solid tumours

Most Recent Events

20 Dec 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Recurrent) in China (Parenteral) (NCT07252414)
26 Nov 2025 GeneScience Pharmaceutical plans a phase I trial in Solid tumours (Late-stage disease, Metastatic disease, Recurrent) in China (Unspecified, Injection) (NCT07252414)
26 Nov 2025 Preclinical trials in Solid tumours in China (Parenteral), before November 2025

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