Drug Profile

Claudin 18.2 targeting CAR-T cell therapy - Ucello Therapeutics

Alternative Names: claudin18.2 CAR-T

Latest Information Update: 12 Dec 2025

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At a glance

Originator Ucello Therapeutics
Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

05 Dec 2025 Preclinical trials in Solid tumours in China (Parenteral) before December 2025
05 Dec 2025 Ucello Therapeutics plans a phase 0 trial for Solid tumours (Late-stage disease, Second-line therapy or greater) in China (Parenteral) in December 2025 (NCT07266311)

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