Drug Profile

GX BP2

Alternative Names: EPDeg™-STAT3; GX-BP2; STAT3-bioPROTAC

Latest Information Update: 28 Jan 2026

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At a glance

Originator Genexine
Class Antineoplastics; Single-domain antibodies; Skin disorder therapies
Mechanism of Action STAT3 transcription factor degraders; STAT6 transcription factor degraders

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

15 Dec 2025 Preclinical trials in Atopic dermatitis in South Korea (SC), before December 2025 (Genexine pipeline, December 2025)
15 Dec 2025 Preclinical trials in Cancer in South Korea (SC), before December 2025 (Genexine pipeline, December 2025)
15 Dec 2025 Pharmacodynamics data from preclinical trials in Atopic dermatitis in released by Genexine (Genexine pipeline, December 2025)

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