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ISM 4808

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Drug Profile

ISM 4808

Alternative Names: ISM-4808

Latest Information Update: 12 Jan 2026

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At a glance

  • Originator InSilico Medicine
  • Developer InSilico Medicine; TaiGen Biotechnology
  • Class Antianaemics; Small molecules
  • Mechanism of Action EGLN1 protein inhibitors; EGLN2 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Anaemia

Most Recent Events

  • 12 Dec 2025 ISM 4808 licensed to TaiGen Biotechnology in China, Macau, Taiwan and Hong Kong
  • 12 Dec 2025 Pharmacodynamics data from the preclinical study in Anemia released by TaiGen Biotechnology
  • 31 Dec 2023 Insilico Medicine announces intention to submit IND to US FDA for Anemia in late 2023 (Insilico Pipeline, December 2025)

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