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TB 003

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Drug Profile

TB 003

Alternative Names: TB-003; TB-003B

Latest Information Update: 12 Jan 2026

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At a glance

  • Originator Therabene
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 9 degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Haematological malignancies; Solid tumours

Most Recent Events

  • 22 Oct 2025 Pharmacodynamics and adverse event data from a preclinical study in Solid tumours and Haematological malignancies presented at the ACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2025 (AACR-NCI-EORTC-2025)
  • 22 Feb 2024 Preclinical trials in Haematological malignancies in USA (Intraperitoneal) Prior to February 2024
  • 22 Feb 2024 Preclinical trials in Solid tumours in USA (Intraperitoneal) Prior to February 2024

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