Drug Profile

GPR68 modulating therapeutic - Cumulus Oncology

Alternative Names: Compound 1 - Cumulus Oncology

Latest Information Update: 12 Jan 2026

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At a glance

Originator leadXpro
Developer Cumulus Oncology; leadXpro
Class Antineoplastics; Small molecules
Mechanism of Action GPR68 protein modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Preclinical Colorectal cancer

Most Recent Events

22 Oct 2025 Preclinical trials in Colorectal cancer in United Kingdom (PO)
22 Oct 2025 Pharmacodynamics data from a preclinical study in Colorectal cancer presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2025 (AACR-NCI-EORTC-2025)

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