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PBX 004

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Drug Profile

PBX 004

Alternative Names: PBX-004

Latest Information Update: 21 Jan 2026

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At a glance

  • Originator Pinotbio
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 22 Oct 2025 Preclinical trials in Solid tumours in South Korea (Parenteral), prior to October 2025
  • 22 Oct 2025 Pharmacodynamics and adverse event data from a preclinical trial in Solid tumour presented at the International Conference on Molecular Targets and Cancer Therapeutics 2025 (AACR-NCI-EORTC-2025)

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