Drug Profile

Cyclin K degrader - Proxygen

Alternative Names: PXG-CycK

Latest Information Update: 16 Jan 2026

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At a glance

Originator Proxygen
Class Antineoplastics; Small molecules
Mechanism of Action Cyclin modulators; Proteolysis

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Preclinical Solid tumours

Most Recent Events

22 Oct 2025 Preclinical trials in Solid tumours in Austria (PO) prior to October 2025
22 Oct 2025 Proxygen plans a clinical trial for Solid tumours
22 Aug 2025 Pharmacodynamics and adverse events data from a preclinical study in Solid tumours presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2025 (AACR-NCI-EORTC-2025)

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