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Amivantamab and hyaluronidase-lpuj injection - Janssen Biotech

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Drug Profile

Amivantamab and hyaluronidase-lpuj injection - Janssen Biotech

Alternative Names: Ami-HC-CF; Ami-LC-MD; Amivantamab admixed with rHuPH20; amivantamab and hyaluronidase-lpuj; amivantamab+hyaluronidase-lpuj; RYBREVANT FASPRO

Latest Information Update: 20 Jan 2026

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At a glance

  • Originator Janssen Biotech
  • Class Antineoplastics; Bispecific antibodies; Glycoside hydrolases; Immunotherapies; Polysaccharide lyases
  • Mechanism of Action Antibody-dependent cell cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Non-small cell lung cancer
  • Phase I Solid tumours

Most Recent Events

  • 17 Dec 2025 Registered for Non-small cell lung cancer (Combination therapy, First-line therapy, Late-stage disease, Metastatic disease) in USA (SC)
  • 17 Dec 2025 Registered for Non-small cell lung cancer (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (SC)
  • 17 Dec 2025 Registered for Non-small cell lung cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (SC)

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