Drug Profile

Laroprovstat/Rosuvastatin - AstraZeneca

Alternative Names: AZD-0780/ZD-4522; Rosuvastatin/Laroprovstat - AstraZeneca; ZD-4522/AZD-0780

Latest Information Update: 13 Feb 2026

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At a glance

Originator AstraZeneca
Class Alcohols; Alkanes; Alkenes; Amines; Antihyperlipidaemics; Carboxylic acids; Cardiovascular therapies; Cyclopentanes; Ethers; Fluorinated hydrocarbons; Fluorobenzenes; Hepatoprotectants; Ketones; Pyridines; Pyridones; Pyrimidines; Small molecules; Sulfonamides; Vascular disorder therapies
Mechanism of Action HMG-CoA reductase inhibitors; PCSK9 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

09 Feb 2026 Chemical structure information added.
05 Jan 2026 Preclinical trials in Unspecified in United Kingdom (PO)
05 Jan 2026 AstraZeneca plans a phase I trial (In volunteers) (PO, Tablet) in March 2026 (NCT07316608)

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