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APG 3288

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Drug Profile

APG 3288

Alternative Names: APG-3288

Latest Information Update: 11 Feb 2026

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At a glance

  • Originator Ascentage Pharma
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Agammaglobulinaemia tyrosine kinase degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Haematological malignancies

Most Recent Events

  • 05 Feb 2026 China Center for Drug Evaluation (CDE) clears investigational new drug (IND) application for APG 3288 in Hematological malignancies
  • 13 Jan 2026 Pharmacodynamics and pharmacokinetics data from a phase I trial in Hematological malignancies released by Ascentage Pharma
  • 06 Jan 2026 Preclinical trials in Haematological malignancies in China (unspecified route) before January 2026

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