Drug Profile

VIB 305

Alternative Names: VIB-305

Latest Information Update: 13 Feb 2026

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At a glance

Originator Vibrant Therapeutics
Class Antineoplastics; Immunoglobulin Fc fragments; Immunotherapies; Recombinant fusion proteins
Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

12 Jan 2026 Phase-I/II clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Second-line therapy or greater) in Australia and China (IV) (NCT07222969)
12 Jan 2026 Preclinical trials in Solid tumours in China (IV) prior to January 2026.
12 Jan 2026 USFDA approves IND application for VIB 305 in Solid tumour

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