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EXV 802

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Drug Profile

EXV 802

Alternative Names: Deraphan; Dextromethorphan + EXV-801; EXV-802

Latest Information Update: 27 Feb 2026

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At a glance

  • Originator Exciva GmbH
  • Class Antitussives; Behavioural disorder therapies; Morphinans; Opioid analgesics; Small molecules
  • Mechanism of Action Cytochrome P-450 CYP2D6 inhibitors; NMDA receptor antagonists; Norepinephrine plasma membrane transport protein inhibitors; Serotonin 2A receptor inverse agonists; Serotonin 2C receptor inverse agonists; Serotonin plasma membrane transport protein inhibitors; Sigma-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Agitation

Most Recent Events

  • 20 Jan 2026 Exciva GmbH plans the phase II/III SERENADA trial for Agitation, in USA, Canada and European union January 2026 (EudraCT2024-517388-22-00), (NCT07284472)

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