Drug Profile

Tumor-activated T cell engager - Bristol Myers Squibb/Janux Therapeutics

Latest Information Update: 03 May 2026

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At a glance

Originator Janux Therapeutics
Class Antineoplastics; Immunoglobulin fragments; Immunotherapies; Peptides; Recombinant fusion proteins
Mechanism of Action Cytotoxic T lymphocyte stimulants; Immunologic cytotoxicity

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

22 Jan 2026 Preclinical trials in Solid tumours in USA (Parenteral) prior to January 2026
21 Jan 2026 Janux Therapeutics and Bristol Myers Squibb announces collaboration and license agreement to develop a tumor-activated therapeutic for solid tumors
21 Jan 2026 Janux Therapeutics plans to file an IND application in USA for solid tumors

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