W 0301
Alternative Names: JAK2V617F-specific LNP-siRNA therapeutic - Antigonie Biosciences; LNP-siJAK2V617F therapeutic - Antigonie Biosciences; W-0301Latest Information Update: 27 Feb 2026
At a glance
- Originator Antigonie Biosciences
- Developer Antigonie Biosciences; NanoVation Therapeutics
- Class Antineoplastics; Small interfering RNA
- Mechanism of Action Janus kinase 2 inhibitors; RNA interference
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Preclinical Myeloproliferative disorders
Most Recent Events
- 06 Dec 2025 Preclinical trials in Myeloproliferative disorders in Canada (IV), prior to December 2025
- 06 Dec 2025 Preclinical trials in Myeloproliferative disorders in United Kingdom (IV), prior to December 2025
- 06 Dec 2025 Pharmacodynamics and adverse events data from preclinical trials in Myeloproliferative disorders presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-2025)