Drug Profile

RioDerm 001

Alternative Names: PEP-TISSEEL; RioDerm-001

Latest Information Update: 03 Mar 2026

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At a glance

Originator RION
Class Exosome therapies
Mechanism of Action Angiogenesis inducing agents; Transforming growth factor beta replacements

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

Highest Development Phases

Phase II Diabetic foot ulcer

Most Recent Events

21 Jan 2026 The US FDA grants a full waiver for the pediatric study of purified exosome product in diabetic foot ulcers
21 Jan 2026 INTENT Biologics plans a pivotal phase III trial for Diabetic foot ulcer in 2026
08 Jan 2026 RioDerm 001 receives Fast Track designation for Diabetic foot ulcer [Topical] in USA

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