Drug Profile

Calcium folinate - AVYXA

Alternative Names: Folinic acid - AVYXA; Vykoura

Latest Information Update: 12 Mar 2026

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At a glance

Originator AVYXA
Class Antianaemics; Antidotes; Chemoprotectants; Chemosensitisers; Formyltetrahydrofolates; Vitamins
Mechanism of Action Tetrahydrofolate dehydrogenase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

03 Feb 2026 Registered for Colorectal cancer (Metastatic disease, Combination therapy) in USA (Parenteral)
03 Feb 2026 Registered for Drug toxicity (In adolescents, In adults, In children, In infants, In neonates) in USA (Parenteral)
03 Feb 2026 Registered for Drug toxicity in USA (Parenteral)

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