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PLX 66140

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Drug Profile

PLX 66140

Alternative Names: PLX-66140

Latest Information Update: 04 Mar 2026

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At a glance

  • Originator Plexium
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 2 degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer; HER2 negative breast cancer

Most Recent Events

  • 12 Feb 2026 Preclinical trials in Cancer in USA (PO) (Plexium pipeline, February 2026)
  • 12 Feb 2026 Preclinical trials in HER2-negative-breast-cancer in USA (PO) (Plexium pipeline, February 2026)

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