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HMPL A 580

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Drug Profile

HMPL A 580

Alternative Names: HMPL-A580

Latest Information Update: 20 Apr 2026

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At a glance

  • Originator HUTCHMED
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 09 Apr 2026 Interim pharmacokinetics and pharmacodynamics data from preclinical trials in Solid tumours released by HUTCHMED
  • 04 Mar 2026 Phase-I/II clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease) in China (Parenteral) (NCT07396584)
  • 09 Feb 2026 Hutchmed plans a phase I/II trial for Solid tumours (Inoperable / Unresectable, Late-stage disease, Metastatic disease) in China in March 2026 (NCT07396584)

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