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AMG 436

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Drug Profile

AMG 436

Alternative Names: AMG-436

Latest Information Update: 03 Apr 2026

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At a glance

  • Originator Amgen
  • Class Antineoplastics
  • Mechanism of Action Undefined mechanism
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 23 Mar 2026 Phase-I clinical trials in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease) in Japan, USA (unspecified route) (NCT07403721)
  • 23 Mar 2026 Phase-I clinical trials in Solid tumours (Monotherapy, Late-stage disease, Metastatic disease) in USA, Japan (unspecified route) (NCT07403721)
  • 11 Feb 2026 Preclinical trials in Solid tumours in USA (unspecified route) before February 2026

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