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Anti-HMGB1 antbody therapeutic - Change Cure

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Drug Profile

Anti-HMGB1 antbody therapeutic - Change Cure

Latest Information Update: 30 Apr 2026

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At a glance

  • Originator Change Cure
  • Class Antibodies; Antidementias
  • Mechanism of Action HMGB1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Alzheimer's disease

Most Recent Events

  • 17 Feb 2026 Preclinical trials in Alzheimer's disease in Japan (unspecified route), prior to February 2026 (Change Cure pipeline, February 2026)

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