Drug Profile

Oxymetazoline - Safety Shot

Alternative Names: DA-020; Topical oxymetazoline - Safety Shot

Latest Information Update: 03 Mar 2026

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At a glance

Originator Safety Shot
Class Alkanes; Benzene derivatives; Eye disorder therapies; Imidazoles; Phenols; Skin disorder therapies; Small molecules; Xylenes
Mechanism of Action Alpha 1 adrenergic receptor agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

Highest Development Phases

Preclinical Alopecia

Most Recent Events

19 Feb 2026 Chemical structure information added.
18 Feb 2026 Safety shot plans a phase-0 Pharmacokinetics trial for Alopecia (In volunteers) in Italy (Topical), (NCT07402330)
12 Feb 2026 Preclinical trials in Alopecia in USA (Topical) prior to February 2026

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