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Dexmedetomidine and propofol - Cyclerion Therapeutics

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Drug Profile

Dexmedetomidine and propofol - Cyclerion Therapeutics

Alternative Names: CYC-126

Latest Information Update: 26 Feb 2026

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At a glance

  • Originator Cyclerion Therapeutics
  • Class General anaesthetics; Phenols; Small molecules
  • Mechanism of Action Alpha 2 adrenergic receptor agonists; GABA A receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Treatment-resistant depressive disorder

Most Recent Events

  • 17 Feb 2026 Clinical trials in Treatment resistant depressive disorder (IV), prior to February 2026
  • 17 Feb 2026 Cyclerion Therapeutics announces intention to submit Clinical Trial Notification (CTN) to the Therapeutic Goods Administration 2026
  • 17 Feb 2026 Cyclerion Therapeutics announces intention to submit IND to US FDA for Treatment resistant depressive disorder

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