Drug Profile

OPN 5877

Alternative Names: OPN-5877

Latest Information Update: 17 Mar 2026

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At a glance

Originator Opna Bio
Class Antineoplastics
Mechanism of Action CREB-binding protein degraders; EP300 protein degraders; IKZF1 protein degraders; IKZF3 protein degraders

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

06 Dec 2025 Preclinical trials in Multiple myeloma in Switzerland (unspecified route) prior to December 2025
06 Dec 2025 Pharmacodynamics data from a preclinical studie sin Multiple myeloma presented at the 67^th American Society of Hematology Annual Meeting and Exposition (ASH-HEM-2025)

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