Drug Profile

VX 272

Alternative Names: VX-272

Latest Information Update: 05 Mar 2026

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At a glance

Originator Vertex Pharmaceuticals
Class Antifibrotics
Mechanism of Action Cystic fibrosis transmembrane conductance regulator modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

27 Feb 2026 Preclinical trials in Cystic fibrosis in USA (PO) before February 2026
25 Feb 2026 Phase-I clinical trials in Cystic fibrosis (In volunteers) in USA (PO) (NCT07437105)
23 Feb 2026 Vertex Pharmaceuticals plans a phase I trial for Cystic fibrosis (In volunteers) (PO) in February 2026 (NCT07437105)

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