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LY 4395089

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Drug Profile

LY 4395089

Alternative Names: LY-4395089

Latest Information Update: 21 May 2026

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At a glance

  • Originator Eli Lilly and Company
  • Class Anti-inflammatories
  • Mechanism of Action Farnesoid X-activated receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Crohn's disease; Ulcerative colitis
  • Preclinical Inflammatory bowel diseases

Most Recent Events

  • 18 May 2026 Eli Lilly and Company plans a phase I pharmacokinetics trial (In volunteers) in USA (PO) in May 2026 (NCT07592572)
  • 04 May 2026 Phase-II clinical trials in Crohn's disease (Treatment-resistant, Combination therapy) in USA (PO) (NCT07483073)
  • 04 May 2026 Phase-II clinical trials in Ulcerative colitis (Treatment-resistant, Combination therapy) in USA (PO) (NCT07483073)

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