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GB 5267

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Drug Profile

GB 5267

Alternative Names: GB-5267

Latest Information Update: 24 Apr 2026

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At a glance

  • Originator Generate Biomedicines; Roswell Park Cancer Institute
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; Interleukin 18 replacements; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Preclinical Ovarian cancer

Most Recent Events

  • 27 Mar 2026 Preclinical trials in Ovarian cancer in USA (Intraperitoneal) prior to March 2026 (Generate Biosciences pipeline, March 2026)
  • 27 Mar 2026 Preclinical trials in Ovarian cancer in USA (IV) prior to March 2026 (Generate Biomedicines pipeline, March 2026)
  • 27 Mar 2026 Generate Biomedicines in collaboration with Roswell Park plans a phase I trial for Ovarian cancer (Second line therapy and greater) in June 2026 (IV/IP; Infusion) (NCT07489287)

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