Drug Profile

SMP 656

Alternative Names: SMP-656

Latest Information Update: 24 Apr 2026

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At a glance

Originator Xiling Lab
Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
Mechanism of Action Apoptosis stimulants; Cadherin modulators; Tubulin polymerisation inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Solid tumours

Most Recent Events

17 Oct 2025 Efficacy and adverse events data from a phase I trial in Solid tumours presented at the 50th European Society for Medical Oncology Congress (ESMO-2025)
27 Dec 2023 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease) in China (Parenteral) (CTR20233290)
31 Aug 2023 Preclinical trials in Solid tumours in China (Parernteral) prior to August 2023

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