Drug Profile

EXP 012

Alternative Names: CTM-013; EXP-012

Latest Information Update: 24 Apr 2026

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At a glance

Originator Lepu Biopharma
Developer Excalipoint Therapeutics
Class Antineoplastics; Immunoglobulin Fc fragments; Immunotherapies; Recombinant fusion proteins; Trispecific antibodies
Mechanism of Action Cytotoxic T lymphocyte stimulants; Immunologic cytotoxicity

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

18 Mar 2026 Preclinical trials in Solid tumours in China (Parenteral) prior to March 2026 (Excalipoint Therapeutics pipeline, March 2026)
01 Mar 2025 Lepu Biopharma enters into a licensing agreement with Excalipoint Therapeutics for CTM 013

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