Mepivacaine interaction
Multiple interactions with and between concomitant antidepressants, antihypertensives, cyclobenzaprine, omeprazole, caffeine and grapefruit juice leading to heart block: case report-
Serious
An event is determined to be serious (based on the ICH definition) when the patient outcome is:
death
life-threatening
hospitalisation
disability
congenital anomaly
other medically important event