Methylphenidate/paroxetine/quetiapine
Lack of efficacy, drug misuse and rebound attention deficit hyperactivity disorder (ADHD) and obsessive compulsive disorder (OCD): case report-
Serious
An event is determined to be serious (based on the ICH definition) when the patient outcome is:
death
life-threatening
hospitalisation
disability
congenital anomaly
other medically important event