Minocycline
Drug induced retinal pigment epithelium (RPE) hyperpigmentation and and blue-gray hyperpigmentation of the lower and upper extremities, as well as of the face, periorbital skin, and sclera: case report-
Serious
An event is determined to be serious (based on the ICH definition) when the patient outcome is:
death
life-threatening
hospitalisation
disability
congenital anomaly
other medically important event