Insulin-like growth factor 1 replacements
Lack of efficacy in Donohue syndrome and Rabson-Mendenhall syndrome leading to progressive decompensation to diabetes mellitus, cataract, liver haemangioma, and impaired hepatic protein synthesis: 3 case reports-
Serious
An event is determined to be serious (based on the ICH definition) when the patient outcome is:
death
life-threatening
hospitalisation
disability
congenital anomaly
other medically important event