Multiple drugs
Lack of efficacy in primary immune thrombocytopenia leading to bleeding, thrombosis, cerebral haemorrhage, myocardial ischaemia, acute coronary syndrome, unstable angina pectoris, petechial gastritis, and melena: case report-
Serious
An event is determined to be serious (based on the ICH definition) when the patient outcome is:
death
life-threatening
hospitalisation
disability
congenital anomaly
other medically important event